Relationship between strain rate imaging and coronary flow reserve in assessing myocardial viability after acute myocardial infarction.

摘要

OBJECTIVES: To evaluate the relationship between strain rate (SR) imaging and coronary flow reserve (CFR) in assessing viability of akinetic myocardium after acute myocardial infarction (MI). METHODS: Forty patients with acute first ST-elevation MI were analyzed. SR imaging and CFR by intracoronary flow measurement were obtained on the same day, 3~5 days after primary percutaneous coronary intervention. Viability of the akinetic myocardium was determined on 6-week echocardiography. RESULTS: Systolic SR (SRs, -0.42 +/- 0.10 vs. -0.35 +/- 0.11 per second, P = 0.03), early diastolic SR (SRe, 0.68 +/- 0.31 vs. 0.41 +/- 0.22 per second, P = 0.003), and systolic strain (Ss, -5.9 +/- 3.4 vs. -2.5 +/- 4.0%, P = 0.04) were greater in akinetic, but viable myocardium of 21 patients than in akinetic and nonviable myocardium of 19 patients. CFR was also higher in patients with akinetic, but viable myocardium (2.0 +/- 0.5 vs. 1.5 +/- 0.5, P < 0.001). SRs, SRe, and Ss were significantly related to CFR (r =-0.50, r = 0.58, r =-0.56, respectively, all P