Biopsy of brain tumors by stereotaxy assisted by tomodensitometry: setting of a new protocol and first clinical applications in dog

摘要

Accurate diagnosis of brain lesions can only be reached by obtaining a tissue sample for histopathologic examination. We describe the design of a prototype device for CT-guided stereotaxic biopsy (CTGSB) of the canine brain which can perform biopsy procedure in 1 cra-lesions. The procedure was initially ascertained in 10 dog cadaver heads in wich 1 ml of a radiolucent paste was injected in a point chosen on the CT images (coordinates: xl, ol, zl). ACT scan was performed again and the center of the injected mass was measured (coordinates: x2, y2, z2). Means and standard deviations (Dx, Dy and Dz) were calculated. Eight dogs demonstrating intracranial tumours were submitted to CTGSB. The procedure has proved to be highly accurate on our trials. Accuracy was 2,9 mm. CTGSB yielded diagnostic samples in the eight dogs. Two complications was observed. CTGSB appears to be a quick, easy and reliable procedure indicated for all unknown brain lesions in the dog.