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The incidence of childhood type 1 diabetes in Ireland and the National Childhood Diabetes Register

机译:爱尔兰和国家儿童糖尿病登记处的儿童1型糖尿病发病率

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摘要

The incidence of Type 1 diabetes (T1D) in childhood and adolescence is increasing globally with few exceptions. To date limited conflicting data has been available regarding diabetes epidemiology in Ireland. We sought to determine the incidence of T1D in those aged under 15 years in the ROI by establishing a prospective national register of incident cases (Irish Childhood Diabetes National Registry (ICDNR)) using a standardised protocol which includes a measure of case ascertainment using capture-recapture methodology. In the period, 489 new cases were identified. All paediatric centres nationally participated. The directly standardised incidence rate was 27.5 per 100,000 per year (95% CIs: 24.0, 30.9) and 26.0 (95% CIs: 22.7, 29.3) in 2008 and 2009 respectively. The ICDNR is widely acceptable, it has confirmed a high incidence of T1D and is vital to monitor changes in disease incidence, optimise resource utilisation and diabetes management in the Irish population.
机译:除少数例外,全球儿童和青少年1型糖尿病(T1D)的发病率正在全球范围内增加。迄今为止,在爱尔兰关于糖尿病流行病学的有限的矛盾数据可用。我们通过使用标准化协议建立前瞻性国家事件病例登记表(爱尔兰儿童糖尿病国家注册中心(ICDNR))来确定ROI中15岁以下人群中T1D的发病率,其中包括采用捕获-重新捕获方法。在此期间,新发现了489个病例。全国所有儿科中心都参加了。在2008年和2009年,直接标准化的发病率分别为每年每100,000 27.5(95%CI:24.0、30.9)和26.0(95%CI:22.7、29.3)。 ICDNR被广泛接受,它已证实T1D的发病率很高,对于监测爱尔兰人群的疾病发病率变化,优化资源利用和糖尿病管理至关重要。

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