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Perioperative corticosteroids administration as a risk factor for pressure ulcers in cardiovascular surgical patients: a retrospective study

机译:围手术期皮质类固醇激素治疗是心血管外科患者压疮的危险因素:一项回顾性研究

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The aim of this study was to investigate the relationship between perioperative corticosteroids administration and the incidence of pressure ulcers (PUs) in cardiovascular surgical patients. A retrospective analysis was performed on data from consecutive patients who had cardiac surgery in 2012. Univariate and multivariate logistic regression analyses were performed to evaluate the relationship between perioperative corticosteroid administration and the incidence of surgery-related PU (SRPU). A total of 286 cardiac surgery patients were included in this study; of these, 47 patients developed 57 SRPUs, an incidence of 16.4% [95% confidence interval (CI): 12.3-21.2%). The SRPU incidence was significantly higher in corticosteroid-administered group compared with groups not receiving corticosteroids (43.8% versus 14.8%, Pearson's chi(2) = 9.209, P = 0.002). The crude odds ratio (OR) was 4.472 (95% CI: 1.576-12.694). After performing multivariate logistic regression analysis, the adjusted OR was 2.808 (95% CI: 1.062-11.769). This result showed that perioperative corticosteroid administration was an independent risk factor for PUs in cardiovascular surgical patients. Therefore, it is recommended that in order to prevent PU perioperative corticosteroids should be administered with caution to cardiovascular surgical patients.
机译:这项研究的目的是调查围手术期使用皮质类固醇激素与心血管外科手术患者的压疮(PU)发生率之间的关系。回顾性分析了2012年连续接受心脏手术的患者的数据。进行了单因素和多因素logistic回归分析,以评估围手术期使用皮质类固醇激素与手术相关PU(SRPU)发生率之间的关系。这项研究总共包括286名心脏外科手术患者。其中47例患者发展了57个SRPU,发生率为16.4%[95%置信区间(CI):12.3-21.2%)。与未接受皮质类固醇的组相比,皮质类固醇给药组的SRPU发生率显着更高(43.8%对14.8%,Pearson's chi(2)= 9.209,P = 0.002)。原油比值比(OR)为4.472(95%CI:1.576-12.694)。进行多元逻辑回归分析后,调整后的OR为2.808(95%CI:1.062-11.769)。该结果表明围手术期给予皮质类固醇激素是心血管外科手术患者PU的独立危险因素。因此,建议为预防PU围手术期使用皮质类固醇激素,对心血管外科手术患者应谨慎使用。

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