Images in pathology: the many faces of hepatocellular carcinoma.

摘要

The component cells of hepatocellular carcinoma can have a myriad of cytological variations, such as pleomorphic giant cells, clear cells, sarcomatoid change, fatty vacuolation, and hyaline inclusion. Multinucleated tumor cells with prominent nucleoli and large hyaline bodies are not infrequent. This hepatocellular carcinoma, arising in a 75-year-old chronic hepatitis B carrier, is particularly rich in malicious cells, which appear as devilish faces aimed at horrifying the pathologists. The figure shows a random selection of these evil beings.