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首页> 外文期刊>Investigative radiology >New Metallic MR Stents for Artifact-Free Coronary MR Angiography: Feasibility Study in a Swine Model.
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New Metallic MR Stents for Artifact-Free Coronary MR Angiography: Feasibility Study in a Swine Model.

机译:用于无伪像的冠状动脉MR血管造影术的新型金属MR支架:猪模型的可行性研究。

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RATIONALE AND OBJECTIVES:: The objective of this study was to investigate the potential for artifact-free coronary magnetic resonance angiography (cMRA) in the presence of dedicated metallic MR stents in vitro and in a swine model. METHODS:: All investigations were performed at 1.5 T, applying a standard cMRA gradient echo sequence with a T2 preparation pulse. Two prototypes of each hand-woven, mechanically woven, and lasered Aachen Resonance Coronary MR Stents made out of an MR-compatible metallic alloy and dilated to 2.5 mm and 4 mm were examined in a water bath. RESULTS:: Artifact behavior was judged independently by 2 radiologists as showing "no artifacts" for all tested stent types. Signal-to-noise ratios inside and outside of the stents were measured yielding a Pearson correlation coefficient of 0.98 (y = 1.22 + 0.92x). Nineteen stents (8 hand woven, 3 mechanically woven, 8 lasered) were deployed in coronary arteries of 19 domestic pigs and were examined by cMRA. Artifact behavior of the stents was analyzed by measuring the signal-to-noise ratio at the stent positions and compared with signal-to-noise ratio measurements outside of the stents, yielding a Pearson correlation coefficient of 0.90 (y = -0.75 + 1.06x). CONCLUSIONS:: All 3 prototypes of coronary MR stents allowed complete visualization of the stent lumen and consequently determination of stent patency by cMRA.
机译:理由和目的:这项研究的目的是研究在体外和猪模型中存在专用金属MR支架的无伪影冠状动脉磁共振血管造影(cMRA)的潜力。方法:所有研究均在1.5 T下进行,应用标准cMRA梯度回波序列和T2准备脉冲。在水浴中检查了由MR兼容金属合金制成的每种手工编织,机械编织和激光化的亚琛共振冠状MR支架的两个原型,该支架分别扩张至2.5 mm和4 mm。结果:两名放射科医师独立判断伪影行为,表明所有测试的支架类型均显示“无伪影”。测量了支架内部和外部的信噪比,得出的皮尔逊相关系数为0.98(y = 1.22 + 0.92x)。在19头家猪的冠状动脉中部署了19个支架(8个手工编织,3个机械编织,8个激光),并通过cMRA进行了检查。通过测量支架位置的信噪比来分析支架的伪影行为,并将其与支架外部的信噪比测量值进行比较,得出的皮尔逊相关系数为0.90(y = -0.75 + 1.06x )。结论:冠状动脉MR支架的所有3个原型都可以对支架腔进行完全可视化,从而通过cMRA确定支架的通畅性。

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