Body mass index modulates postural proteinuria.

摘要

In contrast to constant proteinuria, postural pro-teinuria has been generally regarded as a benign condition [1-4]. However, anecdotal observations suggest that postural proteinuria might sometimes reflect incipient kidney disease [5, 6]. To further address this controversy we recently reassessed 15 subjects with fixed and reproducible postural proteinuria two or more years after the initial diagnosis. After breakfast and after starting an appropriate water load, the subjects came to the clinic. They had been advised to bring along a portion of the first morning urine ("recumbent") for determination of the total protein-to-creatinine ratio (reference value: <30 mg/mmol) [7]. The second morning urine sample was collected for urinary sediment analysis and blood was taken for determination of creatinine.