Antiangiogenic therapy in neovascular age-related macular degeneration.

摘要

Introduction Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in patients over the age of 50 in developed countries. The neovascular form of AMD involves the growth of abnormal blood vessels within the retina and underneath the retina or the retinal pigment epithelium (RPE). Although it occurs in only 15% to 20% of the AMD population, it more commonly results in severe vision loss compared with non-neovascular AMD.l