Use of rocuronium and sugammadex for caesarean delivery in a patient with myasthenia gravis

摘要

Myasthenic patients are known to have increased sensitivity to non-depolarizing neuromuscular blocking agents (NMBA), with decreased sensitivity to, but prolonged muscle relaxation with, succinylcholine.1'2 We describe the first use of sugammadex after modified rapid sequence induction (RSI) using rocuronium for a caesarean delivery in a patient recently diagnosed with myasthenia gravis.A healthy 35-year-old 80 kg woman was admitted at 34 weeks of gestation for worsening dyspnea during an otherwise uneventful pregnancy. She had undergone two previous caesarean deliveries.