Cobalt(II) complexes of the antibiotic sulfadiazine, the X-ray single crystal structure of [Co(C10H9N4O2S)(2)(CH3OH)(2)]

摘要

Cobalt(II) complexes of sulfadiazine formulated as [Co(C10H9N4O2S)(2)(CH3OH)(2)] and [Co(C10H9N4S)(2)(H2O)(2)] have been synthesized and characterized by elemental analysis, infrared and U-V-Vis spectroscopy and magnetic susceptibility measurements. The crystal structures of the complex [Co(C10H9N4O2S)(2)(CH3OH)(2)] and of free sulfadiazine are also reported. The cobalt complex and the sulfadiazine ligand both crystallize in the monoclinic space group, P21/c, with sulfadiazine acting as a bidentate ligand. Cobalt is coordinated to two-sulfonamide nitrogen and the pyrimidine nitrogen of the sulfadiazine. Two molecules of methanol complete the octahedral geometry around the cobalt, with interligand hydrogen bonding between methanol and sulfadiazine. Infrared spectroscopy confirmed the presence of water molecule in the coordination sphere of [Co(C10H9N4S)(2)(H2O)(2)]. The electronic spectra and magnetic moments of both complexes were similar, indicating that both complexes have similar structure. (c) 2006 Elsevier B.V. All rights reserved.