Early polymerization of histoacryl? with BD plastipak? syringes

摘要

Histoacryl? (N-butyl-2-cyanacrylate) is widely used as an embolic agent for the treatment of arteriovenous malformations and arteriov-enous fistula. The glue almost immediately polymerizes when the substance comes in contact with ionic fluids such as blood or with vascular endothelium. To allow a safe injection through a microcatheter the Histoacryl is mixed with ethiodized oils like Lipiodol Ultrafluide? (Guerbet, France). This makes the substance not only radiopaque, but also delays polymerization time and thus allows the interventional-ist to modify the process of polymerization.