The SeQuent Please drug-coated balloon system for percutaneous transluminal coronary angioplasty

摘要

Established methods for treatment of stenotic or occluded arteries are percutaneous transluminal angioplasty and percutaneous transluminal coronary angioplasty (PTCA; or in a more general sense percutaneous coronary intervention [PCI]), subspecialties of image-guided therapy. Despite revolutionizing coronary revascularization, PTCA is associated with persistent difficulties that include vessel recoil and dissection during the procedure and restenosis usually within the first 6 months post-intervention. Restenosis, which is defined as a more than 50% reduction in postproce-dural luminal diameter, and its recurrence rate after PTCA has been shown to generally vary from 30 to 50% [1]. Late lumen loss following PTCA is mainly attributed to negative vascular remodeling, including vessel recoil, shrinkage and restenosis [2].