A Boolean System for Biochemical Data Analysis

摘要

A solution is provided to analyze the results of a series of experiments to demonstrate the effects of combinations of enzyme inputs upon the outputs. It is based upon a Boolean model of the experiments that was published in a textbook on Boolean algebra by another author, to answer certain questions posed by a client biochemist. Because the raw data and the conditions of the experiments are not available to us, the results of the analysis and the answers to the client's questions in this paper, which differ from those of that author, are based solely on his model. Although we use that model so as to compare results, we also point out anomalies that arise in trying to interpret the relationship between the model and the data. The methodology for forming, solving and interpreting Boolean models which is deployed to obtain this solution is in Refs. [2]-[6] inclusive as well as in textbooks on Boolean algebra.