Epigenesis, a new and novel tool is gaining importance and enhancing ground for finding the mystery of genetics in most of medical and psychiatric disorders. Epigenesis or epigenetics is derived from the Greek work coined by Waddington in 1942' refers to interaction of genetic and environmental factors. Changes by this genetic mechanism are developed due to outside influences including environmental factors rather than genetically determined and one that is outside conventional genetics. These changes may remain through cell divisions for the remainder of the cells life or may also last for multiple generations. In psychosomatic disorders particularly the influences of outside factors on genetic material from the very beginning to whole life are observed thus showing the involvement of the ongoing epigenetic process. The underlying mechanism of epigenesis thus involves non-interpreted genes induced by environmentally modified gene expression without altering DNA sequences. (Figure 1) Where responses are mismatched the risk of disease increases.
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