We discuss the large-scale structure of the universe in inflationary cosmology and the implications that it may have for the long-term future of civilizations. Although each civilization is doomed to perish, it may be possible to transmit its accumulated knowledge to future civilizations. We consider several scenarios of this sort. If the cosmological constant is positive, it eventually dominates the universe and bubbles of inflationary phase begin to nucleate at a constant rate. Thermalized regions inside these inflating bubbles will give rise to new galaxies and civilizations. It is possible in principle to send a message to one of them. it might even be possible to send a device whose purpose is to recreate an approximation of the original civilization in the new region. However, the message or device will almost certainly be intercepted by black holes, which nucleate at a much higher rate than inflating bubbles. Formation of new inflating regions can also be triggered by gravitational collapse, but again the probability is low, and the number of attempts required for a positive outcome is enormous. The probability can be higher if the energy scale of inflation is closer to the Planck scale, bur a high energy scale produces a tight bound on the amount of information that can be transmitted. One can try to avoid quantum tunneling altogether, but this requires a violation of quantum inequalities which constrain the magnitude of negative energy densities. However the limits of validity of quantum inequalities are not clear, and future research may show that the required violation is in fact possible. Therein lies the hope for the future of civilizations. [References: 28]
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