Prevention of poststroke cognitive decline: ASPIS - a multicenter, randomized, observer-blind, parallel group clinical trial to evaluate multiple lifestyle interventions - study design and baseline characteristics

摘要

BackgroundCognitive impairment after stroke is a considerable burden to patients and their caregivers and occurs in one-third of stroke survivors. No strategy to prevent cognitive decline after stroke exists thus far. Established vascular risk factors have been associated with cognitive decline and may be a target for therapeutic interventions in stroke survivors.