Whole Brain Irradiation With Hippocampal Sparing and Dose Escalation on Multiple Brain Metastases: A Planning Study on Treatment Concepts

Prokic Vesna; Wiedenmann Nicole; Fels Franziska; Schmucker Marianne; Nieder Carsten; Grosu Anca-Ligia

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Whole Brain Irradiation With Hippocampal Sparing and Dose Escalation on Multiple Brain Metastases: A Planning Study on Treatment Concepts

机译：全脑辐射与海马节育和多发脑转移的剂量递增：治疗概念的规划研究

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Purpose: To develop a new treatment planning strategy in patients with multiple brain metastases. The goal was to perform whole brain irradiation (WBI) with hippocampal sparing and dose escalation on multiple brain metastases. Two treatment concepts were investigated: simultaneously integrated boost (SIB) and WBI followed by stereotactic fractionated radiation therapy sequential concept (SC).

机译：目的：为患有多种脑转移的患者制定新的治疗计划策略。目的是进行全脑照射（WBI）并保留海马区，并在多个脑转移瘤上增加剂量。研究了两种治疗方案：同时进行联合增强（SIB）和WBI，然后进行立体定向分次放射疗法序贯方案（SC）。

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《International Journal of Radiation Oncology, Biology, Physics》 |2013年第1期|共7页
作者
Prokic Vesna; Wiedenmann Nicole; Fels Franziska; Schmucker Marianne; Nieder Carsten; Grosu Anca-Ligia;
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正文语种 eng
中图分类放射医学;
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1. Whole Brain Irradiation With Hippocampal Sparing and Dose Escalation on Multiple Brain Metastases: A Planning Study on Treatment Concepts [J] . Prokic Vesna, Wiedenmann Nicole, Fels Franziska, International Journal of Radiation Oncology, Biology, Physics . 2013,第1期

机译：全脑辐射与海马节育和多发脑转移的剂量递增：治疗概念的规划研究
2. Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) – a phase II prospective randomized multicenter trial (NOA-14, ARO 2015–3, DKTK-ROG) [J] . Anca-Ligia Grosu, Lars Frings, Iryna Bentsalo, BMC Cancer . 2020,第1期

机译：全脑照射与海马备件和转移剂量升级：神经认知检测和生物成像（Hipporad） - II期前瞻性随机化多中心试验（NOA-14，2015-3，DKTK-ROG）
3. Local Tumor Control and Survival after hippocampal-sparing Whole-Brain Radiotherapy and Dose Escalation on multiple cerebral Metastases [J] . Popp I, Rau S., Hintz M., Strahlentherapie und Onkologie . 2019,第Suppla1期

机译：局部肿瘤对照和生存在海马滥本后全脑放射治疗和多次脑转移的剂量升级
4. Determination of Dose Escalation Region in Malignant Brain tumors for Radiation Treatment Planning Based on Apparent Diffusion Coefficient Map [C] . J.Y Park, KJ Ahn, D.C Woo, World congress on medical physics and biomedical engineering;International congress of the IUPESM . 2011

机译：基于表观扩散系数图确定恶性脑肿瘤剂量递增区域以进行放射治疗计划
5. Treatment of Multiple Brain Metastases Using Stereotactic Radiosurgery with Single-Isocenter Volumetric Modulated Arc Therapy: Comparison with Conventional Dynamic Conformal Arc and Static Beam Stereotactic Radiosurgery. [D] . Huang, Chi. 2012

机译：立体定向放射外科与单等中心容积调制电弧疗法一起治疗多发性脑转移：与常规动态等角弧和静态束立体定向放射外科的比较。
6. Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) – a phase II prospective randomized multicenter trial (NOA-14 ARO 2015–3 DKTK-ROG) [O] . Anca-Ligia Grosu, Lars Frings, Iryna Bentsalo, 2020

机译：海马全脑照射和转移瘤剂量增加：神经认知测试和生物影像学（HIPPORAD）– II期前瞻性随机多中心试验（NOA-14ARO 2015-3DKTK-ROG）
7. Local Tumor Control and Survival after Hippocampus-Avoidance Whole-Brain Irradiation and Dose Escalation on Multiple Brain Metastases [O] . I. Popp, S. Rau, M. Hintz, 2019

机译：海马局部肿瘤对照和生存 - 避免全脑照射和多重脑转移的剂量升级

Whole Brain Irradiation With Hippocampal Sparing and Dose Escalation on Multiple Brain Metastases: A Planning Study on Treatment Concepts

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