A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model

Lee Jaejoon; Hong Eun Chung; Jeong Hyemin; Hwang Ji Won; Kim Hyungjin; Bae Eun-Kyung; Ahn Joong Kyong; Choi Yoon-La; Han Jungho; Cha Hoon-Suk; Koh Eun-Mi

首页> 外文期刊>International journal of rheumatic diseases >A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model

【24h】

A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model

机译：新型组蛋白脱乙酰基酶6选择性抑制剂可抑制胶原蛋白抗体诱发的关节炎小鼠模型中的滑膜炎症和关节破坏

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

AimTo investigate the effects of Tubastatin A, a selective histone deacetylase-6 inhibitor, on synovial inflammation and joint destruction in a collagen antibody-induced arthritis (CAIA) mouse model.

机译：目的研究选择性组蛋白脱乙酰基酶-6抑制剂Tubastatin A对胶原抗体诱导的关节炎（CAIA）小鼠模型中滑膜炎症和关节破坏的影响。

著录项

来源
《International journal of rheumatic diseases》 |2015年第5期|共10页
作者
Lee Jaejoon; Hong Eun Chung; Jeong Hyemin; Hwang Ji Won; Kim Hyungjin; Bae Eun-Kyung; Ahn Joong Kyong; Choi Yoon-La; Han Jungho; Cha Hoon-Suk; Koh Eun-Mi;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类全身性疾病;
关键词
rheumatoid arthritis; tubastatin; erosion; collagen antibody-induced arthritis;

机译：类风湿关节炎;他汀类药物;侵蚀;胶原抗体诱导的关节炎;

相似文献

外文文献
中文文献
专利

1. A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model [J] . Lee Jaejoon, Hong Eun Chung, Jeong Hyemin, International journal of rheumatic diseases . 2015,第5期

机译：新型组蛋白脱乙酰基酶6选择性抑制剂可抑制胶原蛋白抗体诱发的关节炎小鼠模型中的滑膜炎症和关节破坏
2. Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model. [J] . Nasu Y, Nishida K, Miyazawa S, Osteoarthritis and cartilage . 2008,第6期

机译：组蛋白脱乙酰基酶抑制剂曲古他汀A在胶原蛋白抗体诱导的关节炎小鼠模型中抑制滑膜炎症和随后的软骨破坏。
3. The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis [J] . PetersM.A., WendholtD., StrietholtS., Arthritis and Rheumatism . 2012,第5期

机译：类风湿关节炎小鼠模型中α2β1整合素的丢失抑制关节炎症和软骨破坏
4. The Histone Deacetylase Inhibitor Scriptaid Improves the Expression Pattern of TIF1β In Cloned Outbred Mouse Embryos. [C] . N.T.T. Tram, N.H. Kieu Linh, N.T. Minh International Conference on the Development of Biomedical Engineering in Vietnam . 2018

机译：组蛋白脱乙酰化酶抑制剂Scriptaid改善了克隆扩出小鼠胚胎中TIF1β的表达模式。
5. The effect of acute nicotine administration on the progression of collagen induced arthritis and the joint proteome in male and female DBA/1J mouse animal models. [D] . John, Nicole. 2006

机译：在雄性和雌性DBA / 1J小鼠动物模型中，急性尼古丁给药对胶原蛋白诱发的关节炎和关节蛋白质组进展的影响。
6. IL-1β in Irrigation Fluid and MRNA Expression in Synovial Tissue of the Knee Joint as Therapeutic Markers of Inflammation in Collagen Antibody-Induced Arthritis [O] . Wei-Tso Chia, Li-Tzu Yeh, Yuan-Wu Chen, 2009

机译：胶原蛋白诱导的关节炎的炎症治疗指标为灌溉液中的IL-1β和膝关节滑膜组织中的MRNA表达
7. Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model [O] . Nasu Y., Nishida K., Miyazawa S., 2008

机译：Trichostatin A，一种组蛋白脱乙酰基酶抑制剂，在胶原蛋白抗体诱发的关节炎小鼠模型中抑制滑膜炎症和随后的软骨破坏

A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model

摘要

著录项

相似文献

相关主题

期刊订阅