Radiation-induced hematopoietic myelosuppression and genotoxicity get significantly countered by active principles of Podophyllum hexandrum: A study in strain 'A' mice

Verma Savita; Gupta Manju Lata

首页> 外文期刊>International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations >Radiation-induced hematopoietic myelosuppression and genotoxicity get significantly countered by active principles of Podophyllum hexandrum: A study in strain 'A' mice

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Radiation-induced hematopoietic myelosuppression and genotoxicity get significantly countered by active principles of Podophyllum hexandrum: A study in strain 'A' mice

机译：六倍体鬼臼的活性成分可显着抵消辐射诱导的造血性骨髓抑制和遗传毒性：“ A”品系小鼠的一项研究

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Purpose : To investigate the protective role of a novel formulation, prepared by a combination of three active principles isolated from Podophyllum hexandrum (G-002M), against radiation-mediated hematopoietic suppression and cytogenetic aberrations in lethally irradiated mice.

机译：目的：研究通过从六倍体鬼臼（G-002M）分离的三种活性成分的组合制备的新型制剂对经致死剂量照射的小鼠的辐射介导的造血抑制和细胞遗传学异常的保护作用。

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《International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations》 |2015年第9期|共14页
作者
Verma Savita; Gupta Manju Lata;
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正文语种 eng
中图分类放射医学;
关键词
Podophyllum hexandrum; ionizing radiation; radioprotection; chromosomal aberrations; micronuclei; erythropoietin;

机译：鬼臼;电离辐射;放射防护;染色体畸变;微核;促红细胞生成素;

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1. Radiation-induced hematopoietic myelosuppression and genotoxicity get significantly countered by active principles of Podophyllum hexandrum: A study in strain 'A' mice [J] . Verma Savita, Gupta Manju Lata International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations . 2015,第9期

机译：六倍体鬼臼的活性成分可显着抵消辐射诱导的造血性骨髓抑制和遗传毒性：“ A”品系小鼠的一项研究
2. Alleviation of radiation-induced genomic damage in human peripheral blood lymphocytes by active principles of Podophyllum hexandrum: An in vitro study using chromosomal and CBMN assay [J] . DuttaS., GuptaM.L. Mutagenesis . 2014,第2期

机译：鬼臼的活性成分减轻人外周血淋巴细胞辐射引起的基因组损伤：使用染色体和CBMN分析的体外研究
3. Alleviation of radiation-induced genomic damage in human peripheral blood lymphocytes by active principles of Podophyllum hexandrum: An in vitro study using chromosomal and CBMN assay [J] . DuttaS., GuptaM.L. Mutagenesis . 2014,第2期

机译：Podophyllum Hexandrum活性原理对人外周血淋巴细胞的辐射诱导的基因组损伤：使用染色体和CBMN测定的体外研究
4. Study on Genotoxicity of Formaldehyde on the Liver Cells in Mice [C] . Gao Na-na, Chang Qing, Liu Dan-dan, The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议）论文集 . 2009

机译：甲醛对小鼠肝细胞的遗传毒性研究
5. A dietary ethanol protocol for Cyp2e1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene. [D] . Daiker, Davis Hollingsworth. 1999

机译：用于在CD-1小鼠中诱导Cyp2e1的饮食乙醇方案及其在研究低水平苯的遗传毒性，免疫毒性和代谢中的应用。
6. REC-2006—A Fractionated Extract of Podophyllum hexandrum Protects Cellular DNA from Radiation-Induced Damage by Reducing the Initial Damage and Enhancing Its Repair In Vivo [O] . Pankaj Chaudhary, Sandeep Kumar Shukla, Rakesh Kumar Sharma 2011

机译：REC-2006 —鬼臼的分级提取物通过减少初始损伤并增强体内修复作用保护细胞DNA免受辐射诱导的损伤
7. REC-2006—A Fractionated Extract of Podophyllum hexandrum Protects Cellular DNA from Radiation-Induced Damage by Reducing the Initial Damage and Enhancing Its Repair In Vivo [O] . Chaudhary, Pankaj, Shukla, Sandeep Kumar, Sharma, Rakesh Kumar 2011

机译：REC-2006 —鬼臼的分级提取物通过减少初始损伤并增强体内修复作用，保护细胞DNA免受辐射诱导的损伤

Radiation-induced hematopoietic myelosuppression and genotoxicity get significantly countered by active principles of Podophyllum hexandrum: A study in strain 'A' mice

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