Dependence of radiation-induced H2AX phosphorylation on histone methylation: Evidence from the chromatin immunoprecipitation assay

Sak Ali; Kuebler Dennis; Bannik Kristina; Groneberg Michael; Stuschke Martin

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Dependence of radiation-induced H2AX phosphorylation on histone methylation: Evidence from the chromatin immunoprecipitation assay

机译：辐射诱导的H2AX磷酸化对组蛋白甲基化的依赖性：染色质免疫沉淀测定的证据

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摘要

Purpose: To evaluate ionizing radiation (IR)-induced DNA damage response within euchromatic and heterochromatic regions.

机译：目的：评估在常色和异色区域内电离辐射（IR）引起的DNA损伤响应。

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来源
《International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations》 |2015年第4期|共8页
作者
Sak Ali; Kuebler Dennis; Bannik Kristina; Groneberg Michael; Stuschke Martin;
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正文语种 eng
中图分类放射医学;
关键词
H2AX; ChIP; radiation; histone methylation; heterochromatin; euchromatin; DNA double-strand breaks;

机译：H2AX;ChIP;辐射;组蛋白甲基化;异染色质;常染色质;DNA双链断裂;

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1. Dependence of radiation-induced H2AX phosphorylation on histone methylation: Evidence from the chromatin immunoprecipitation assay [J] . Sak Ali, Kuebler Dennis, Bannik Kristina, International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations . 2015,第4期

机译：辐射诱导的H2AX磷酸化对组蛋白甲基化的依赖性：染色质免疫沉淀测定的证据
2. Phosphorylation of H2AX histone as indirect evidence for double-stranded DNA breaks related to the exchange of nuclear proteins and chromatin remodeling in Chara vulgaris spermiogenesis [J] . Wojtczak A, Poplonska K, Kwiatkowska M Protoplasma: An International Journal of Cell Biology . 2008,第3a4期

机译：H2AX组蛋白的磷酸化作为双链DNA断裂的间接证据，与寻常型Chara精子发生过程中核蛋白的交换和染色质重塑有关
3. Histone H2AX phosphorylation in normal human cells irradiated with focused ultrasoft X rays: Evidence for chromatin movement during repair [J] . Hamada N, Schettino G, Kashino G, Radiation Research: Official Organ of the Radiation Research Society . 2006,第1aPta1期

机译：聚焦超软X射线照射的正常人细胞中的组蛋白H2AX磷酸化：修复过程中染色质运动的证据
4. Development of a Quantitative SRM Assay for Histone H2AX Ser139 Phosphorylation, a Key Regulator of the DNA Damage Response (DDR) [C] . V Lunyak, A Prakash, M Athanas, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：组蛋白H2AX Ser139磷酸化的定量SRM测定，DNA损伤响应的关键调节器（DDR）
5. Regulation of H2AX phosphorylation density around a defined double stranded DNA break in chromatin. [D] . Savic, Velibor. 2009

机译：围绕染色质中定义的双链DNA断裂的H2AX磷酸化密度的调节。
6. Histone H2AX phosphorylation in response to changes in chromatin structure induced by altered osmolarity [O] . Jennifer Baure, Atefeh Izadi, Vannina Suarez, -1

机译：组蛋白H2AX磷酸化响应渗透压改变引起的染色质结构变化
7. Expression and Radiation-induced Phosphorylation of Histone H2AX in Mammalian Cells [O] . KAYO YOSHIDA, SHU-HEI YOSHIDA, CHIKASHI SHIMODA, 2003

机译：哺乳动物细胞中组蛋白H2AX的表达和辐射诱导的磷酸化
8. Histone Phosphorylation Related to Chromatin Strucuture [R] . Gurley, L. R., Walters, R. A., Hildebrand, C. E., 1976

机译：与染色质结构相关的组蛋白磷酸化

Dependence of radiation-induced H2AX phosphorylation on histone methylation: Evidence from the chromatin immunoprecipitation assay

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