Height correlations between parents and offspring in achondroplasia population

摘要

Growth is a result of the continuous and complex interaction between heredity and environment. The degree, to which height is controlled by genotype, when environmental circumstances are adequate, is reflected in the variation of height within families compared to the variation of height among a population. The range of variation in adult height, represented by +-2 SD around the mean, is about 25 cm for most male population, 16 cm among brothers and 1.6 cm among monozygotic twins brought up together [Tanner, 1978].