An old drug against giardiasis: mebendazole as a treatment option.

摘要

Lalle recently reviewed Giardiasis in the Post Genomic Era: Treatment, Drug Resistance and Novel Therapeutic Perspectives [1], and did not include mebendazole (MBZ) as an effective drag against giardiasis. Certainly, even when MBZ was found to be ineffective by Gascon et al. [2], and di Martino et al. [3], its use has been proposed for some authors as a potential candidate for this parasitic disease since it has evident effects in vitro and in vivo. Various drag regimens have been assayed against giardiasis, mainly in children, to find out the best option in this relatively novel indication (see Table 1). According to the results obtained, MBZ appears to be also an important option for the treatment of G. lamblia infections, at least, in children.