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Antemortem pathological changes suggestive of reactive and degenerative arthritic disorders

机译:前反应性病理改变提示反应性和退行性关节炎疾病

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摘要

The present case displays severe antemortem skeletal malformations suggestive of antemortem reactive arthritis (ReA), spondyloarthropathies and diffuse idiopathic skeletal hyperostosis (DISH). The ossified anterior longitudinal ligament on the right side of the thoracic vertebral bodies, with the presence of extraspinal enthesophytes, together indicates DISH. Fused lumbar vertebrae with costovertebral and sacroiliac joint fusion, combined with numerous large enthesophytes collectively suggest ankylosing spondylosis and ReA. Finally, some vertebrae showed evidence of age related osteoarthritis. However, the anatomical evidence for these conditions displays some inconsistencies with the known pathogenesis; therefore, a definitive account of this individual's antemortem condition remains uncertain. As no biological or medical information is known about the individual, skeletal morphology, irregular skeletal fusion and the presence of enthesophytes have been collectively used to propose the antemortem disorders that appear to have affected this individual's skeleton.
机译:本病例显示严重的死前骨骼畸形,提示死前反应性关节炎(ReA),脊椎关节病和弥漫性特发性骨骼肥大(DISH)。胸椎右侧右侧的骨化前纵韧带伴有脊柱外植体,共同提示DISH。融合性腰椎与肋椎和sa关节融合,再加上大量大型的附生植物,共同提示强直性脊柱病和ReA。最后,一些椎骨显示出与年龄有关的骨关节炎的证据。但是,这些情况的解剖学证据与已知的发病机制存在一些矛盾之处。因此,仍不确定该人的死前状况的确切说明。由于尚无关于该个体的生物学或医学信息,因此已集体使用骨骼形态,不规则骨骼融合和存在的附生植物来提出似乎已影响该个体骨骼的前驱疾病。

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