PEG spacer gel and adaptive planning vs single plan in external prostate radiotherapy-clinical dosimetry evaluation

摘要

Objective: Spacer gel is used to reduce the rectal dose in prostate radiotherapy. It is injected to increase the distance between the prostate and rectum. During the course of external radiotherapy treatment, physiological changes in rectal volume exist. When using polyethylene glycol material, such as DuraSeal (R) (Covidien, Mansfield, MA), gel resorption also occurs. Together, these factors alter the original dose plan distribution.