The diagnostic value of FDG-PET cannot be judged by iliac bone marrow biopsy

摘要

We read with great interest a recent publication by Muzahir et al on the value of 18-fludeoxyglucose-positron emission tomography (FDG-PET)/CT in the detection of bone marrow involvement (BMI) in Hodgkin's lymphoma (HL). However, we cannot agree with the authors on the definition of BMI. We believe that the data were not reliable because the authors defined a positive bone marrow lesion based solely on a positive finding on iliac bone marrow biopsy (BMB), and because the authors regarded diffuse FDG uptake in bone marrow as a positive PET finding.