A Study on the Synthesis and Antibacterial Evaluation of Certain Copolyesters Containing Bischalcone Moiety in the Main Chain

摘要

Four copolyesters were synthesized by making use of succinyl chloride, and azelaic acid dichloride with the common diol (diol-I) 1,1 '-methylene dinaphthol and the varying diol (diol-II) namely 3,3'-(1,4-phenylene)bis(1-(4-hydroxyphenyl)prop-2-en-1-one) (THAP) and 3,3'-(1,4-phenylene)bis(1-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one) (TMAP) by phase transfer catalyzed polycondensation. Acid catalyzed Claisen-Schmidt reaction was employed to synthesize the two varying diols. These copolyesters were characterized by solubility data and viscosity values. The microstructure of the repeating unit present in the copolyester backbone was confirmed by FT-IR, ~1H-NMR and ~(13)C-NMR spectra. These copolyesters exhibited prospective antibacterial activity against certain pathogenic bacteria.