Clinical significance of active myeloperoxidase in carotid atherosclerotic plaques.

摘要

Assessment of vulnerable carotid artery plaques is a major unresolved issue. Patients presenting unstable angina have evidence of unstable carotid artery plaque [1] suggesting systemic vascular vulnerability [2], Neutrophil myeloperoxidase (MPO) is a powerful producer of oxidant molecule [3], MPO level is higher in patients with coronary artery disease and in patients undergoing percutaneous coronary intervention for unstable coronary syndrome compared to stable patients [4,5], carrying predictive value of adverse outcome [6].