Acute immune-mediated thrombocytopenic purpura related to Toxoplasma gondii infection

摘要

Acute toxoplasmosis has a benign course in immunocompetentadult patients. However, complications following infection can occur in congenital disease, immunocompromised patients, or with the ocular form. Hematological disorders associated with acute toxoplasmosis are characterized by the mononucleosis-like form of the disease with leukopenia and lymphocytosis, including atypical lymphocytes in some cases. Anemia and thrombocytopenia are extremely rare events.The association of toxoplasmosis and low platelets has been described in the congenital form of the disease, whereas acute thrombocytopenic purpura has rarely been described. This disorder can be a complication of the primary infection with poor outcome due to the risk of severe bleeding.We describe a case of acute immune-mediated thrombocytopenic purpura (IMTP) related to Toxoplasma gondii infection in an immunocompetent adult patient.