Increased risk of coronary heart disease in male patients with central serous chorioretinopathy: Results of a population-based cohort study

摘要

Actually we used two survival analyses in the paper: a Kaplan-Meier (KM) plot with log-rank test (figure 1), and stratified Cox regression (table 2). Among the 815 cases and 4075 controls, 41 cases and 164 controls had pre-coronary heart disease (CHD). In the KM analysis, we excluded only those with pre-CHD, and the corresponding (unadjusted) p value from log-rank test for central serous chorioretinopathy (CSCR) is 0.002. However, in stratified Cox regression, we did exclude 41 cases along with their fivefold matched controls (as stated in the legend of figure 1, 774 cases and 3870 controls were used), and came out with a hazard rate ratio for CSCR of 1.61, with adjusted p value 0.009.