Early-onset severe growth restriction and placental abruption associated with Breus mole.

摘要

An 18-year-old primigravida with raised a-fetoprotein levels at 15 weeks of pregnancy displayed reduced amniotic fluid volume (amniotic fluid index [AFI], 11 cm) and bulky placenta at her 20-week mid-trimester scan.A repeat scan at 24 + 6 weeks showed reduced AFI (13 cm), absent end diastolic flow, bulky placenta, and no fetal growth-with significant asymmetric growth restriction (estimated fetal weight, 341 g) (Fig. 1). Because of early-onset severe growth restriction and absent end diastolic flow, the woman was informed of the poor fetal prognosis and received 2 doses of steroid to enhance pulmonary maturity.