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Late and very late initial probing for congenital nasolacrimal duct obstruction: what is the cause of failure?

机译:先天性鼻泪管梗阻的早期和晚期检查:失败的原因是什么?

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AIMS: To find the cure rate of late (second year of age) and very late (3-5 years of age) initial probing for congenital nasolacrimal duct obstruction (CNLDO) and to identify the factors contributing to the failure rate of the probing in older children. METHODS: In a prospective interventional case series study, 169 eyes of 125 consecutive patients (1-5 years old) with CNLDO underwent probing under general anaesthesia. Cure was defined as absence of tearing and discharge in the affected eye. RESULTS: 138 eyes of 101 patients aged 13-60 months (mean 23.4 (SD 10.2)) were included. Of 15 eyes (10.8%) with complex CNLDO, 80% presented after 24 months of age (p<0.0001). The cure rate was 89% in patients 13-24 months of age and 72% after the age of 24 months (p = 0.01). It was 90.2% in the membranous and 33.3% in the complex CNLDO in both late and very late probing (p<0.0001). There was a high correlation (r = 0.97) and no significant difference between the cure rate at 1 week and final follow up. CONCLUSION: Accumulation of the complex CNLDO is the main risk factor for failure of probing in the older children. The outcome of the nasolacrimal duct probing at 1 week follow up is highly indicative of the final outcome.
机译:目的:寻找先天性鼻泪管阻塞(CNLDO)的晚期(第二年)和非常晚期(3-5岁)的治愈率,并确定导致该方法失败的因素大一点的孩子。方法:在一项前瞻性介入病例系列研究中,在全身麻醉下对125例连续的CNLDO患者(1-5岁)的169眼进行了探查。治愈的定义是患眼没有流泪和流泪。结果:纳入101名年龄在13-60个月的患者的138只眼(平均23.4(标准差10.2))。在15眼(10.8%)的复合性CNLDO中,有80%在24个月大后出现(p <0.0001)。 13-24个月大的患者治愈率为89%,24个月大的患者治愈率为72%(p = 0.01)。在晚期和非常晚期的探查中,在膜状中的检出率为90.2%,在复杂的CNLDO中为33.3%(p <0.0001)。有很高的相关性(r = 0.97),在第1周的治愈率和最终的随访之间没有显着差异。结论:复杂CNLDO的积累是较大儿童探测失败的主要危险因素。随访1周时鼻泪管探测的结果高度指示最终结果。

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