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Is body mass index a risk factor for motor vehicle driver injury? A cohort study with prospective and retrospective outcomes.

机译:体重指数是否是导致机动车驾驶员受伤的危险因素?一项具有前瞻性和回顾性结果的队列研究。

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OBJECTIVE: To investigate the association between risk of motor vehicle driver injury and body mass index (BMI). METHODS: In a cohort study of 10 525 New Zealand men and women, BMI was assessed in 1992-1993 (baseline), and data on deaths and hospitalizations for motor vehicle driver injury were obtained by record linkage to national health databases for the period 1988-1998. Hazard ratios (HR) and CI were estimated by Cox regression. RESULTS: During a mean 10.3 years of follow-up, 139 fatal and non-fatal driver injury cases occurred (85 before baseline and 54 after). A U-shaped association was observed between driver injury risk and BMI, both crudely and after adjustment for covariates, which included age, sex, driving exposure, and alcohol intake (P-values for quadratic trend /=28.7 kg/m(2); HR = 2.00, 95% CI: 1.18-3.39) and lowest (<23.5 kg/m(2); HR = 2.17, 95% CI: 1.27-3.73) quartiles of BMI were twice as likely to have experienced a driver injury during the follow-up period as participants in the reference quartile (25.9-28.6 kg/m(2); HR = 1.00). CONCLUSION: Further research is needed to corroborate or refute the hypothesis that BMI is a risk factor for serious motor vehicle driver injury.
机译:目的:探讨机动车驾驶员受伤风险与体重指数(BMI)之间的关系。方法:在一项针对10525名新西兰男女的队列研究中,对BMI进行了1992-1993年评估(基线),并通过与1988年国家卫生数据库的记录链接获得了机动车驾驶员受伤的死亡和住院数据。 -1998。危险比(HR)和CI通过Cox回归估算。结果:在平均10.3年的随访期间,发生了139例致命和非致命的驾驶员伤害病例(基线前85例,术后54例)。粗略地发现和在调整协变量后,驾驶员伤害风险与BMI之间呈U形关联,协变量包括年龄,性别,驾驶暴露和饮酒(二次趋势的P值 / = 28.7 kg / m(2); HR = 2.00,95%CI:1.18-3.39)和最低(<23.5 kg / m(2); HR = 2.17,95%CI:1.27- 3.73)在随访期间,BMI四分位数遭受驾驶员伤害的可能性是参考四分位数的参与者的两倍(25.9-28.6 kg / m(2); HR = 1.00)。结论:需要进一步的研究来证实或反驳体重指数是严重的机动车驾驶员受伤危险因素的假设。

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