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GuardIVa: a novel antimicrobial haemostatic IV dressing: Part 1.

机译:GuardIVa:一种新型的抗菌止血IV敷料:第1部分。

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摘要

HemCon GuardIVa(R) is a hydrophilic polyurethane sponge dressing impregnated with the broad spectrum antimicrobial agent chlorhexidine gluconate (CHG) and a proprietary formulation of the haemostatic agent oxidized cellulose. The intended use of the dressing is to absorb exudate, cover and protect catheter sites. Some common applications include intravenous (IV) catheters, other intravenous catheters and percutaneous devices. GuardIVa is also the only IV site dressing indicated to control surface bleeding from percutaneous access sites. A clinical study in healthy human volunteers has demonstrated the ability of the GuardIVa dressing to significantly suppress skin flora re-growth. The antimicrobial and haemostatic efficacy of the GuardIVa dressing and its effects on wound healing have also been demonstrated by independent laboratories in a number of in-vitro and in-vivo tests. These data suggest that GuardIVa would be an effective component as part of a catheter site regimen to help reduce skin microbial colonization, provide sustained antimicrobial protection against the major organisms responsible for catheter-related blood stream infections (CR-BSIs) and prevent the risk of CR-BSIs.
机译:HemCon GuardIVa(R)是一种亲水性聚氨酯海绵敷料,其浸渍有广谱抗菌剂葡萄糖酸氯己定(CHG)和止血剂氧化纤维素的专有配方。敷料的预期用途是吸收渗出液,覆盖并保护导管部位。一些常见的应用包括静脉(IV)导管,其他静脉导管和经皮设备。 GuardIVa也是唯一可控制经皮进入部位表面出血的IV部位敷料。在健康的人类志愿者中进行的一项临床研究表明,GuardIVa敷料具有显着抑制皮肤菌群重新生长的能力。独立实验室在许多体外和体内试验中也证明了GuardIVa敷料的抗微生物和止血功效及其对伤口愈合的影响。这些数据表明,GuardIVa将成为导管部位治疗方案的有效组成部分,以帮助减少皮肤微生物定植,对引起导管相关血流感染(CR-BSI)的主要生物体提供持续的抗菌保护,并防止患上导管静脉炎的风险。 CR-BSI。

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