The impact of a taurine-free drink enhanced with citicoline and other natural ingredients on electrophysiological markers of mental alertness was examined. 10 healthy adult participants enrolled in a double-blind, placebo-controlled crossover study, and were randomised to receive either placebo or the citicoline supplement on the first visit. Measures of electrical brain activity using electroencephalogram (EEG) were collected 30 min after consuming the beverage. 7 days after the initial assessment, participants completed the alternative condition (placebo or citicoline beverage). Compared to placebo, significant improvements were found in frontal alpha EEG and N100 event related potentials (ERP) associated with the citicoline-enhanced supplement. These preliminary findings suggested that a novel brain drink containing compounds known to increase choline in the brain significantly improved attention, as measured by ERP and EEG. These findings also suggested that a viable and alternative brain supplement without potential compounds, such as taurine, may augment attentional mechanisms in healthy individuals.
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