Parametric Proportional Hazards Model with Time Dependent Covariates for Nonproportional Hazards

摘要

The main modelling method used in survival analysis is the Cox regression model that has an assumption of proportional hazards. In the violation of proportional hazards, usage of different survival models is suggested. In this study, the parametric proportional hazards models with time dependent covariates are investigated under nonproportional hazards with a known survival time distribution. The examined models are applied to a real survival data and the results are presented with those obtained with the Cox and parametric proportional hazards models.