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首页> 外文期刊>International journal of computational biology and drug design >Software for the interactive visualisation of experimental data in the genomic context.
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Software for the interactive visualisation of experimental data in the genomic context.

机译:用于在基因组环境中交互式可视化实验数据的软件。

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摘要

Time-lagging in expression occurs when a gene's expression triggers a delayed expression in its co-regulated or anti-co-regulated peers. Arbitrary time-lagging also might appear due to experiment or measurement error. Traditional methods will either under-estimate or completely miss such correlation, which is not unusual and plays important roles. Since the traditional similarity measurement cannot capture the true relationship, a simple time-lagging captured algorithm integrated with some existing time-lagging and similarity measurement techniques is proposed with parallel implementation. Improvements such as isolation of experimental conditions and weighted averages are used to achieve better accuracy and give user flexibility to differentiate different experiments.
机译:当基因的表达在其共同调控或反共同调控的同伴中触发延迟表达时,就会出现表达时滞。由于实验或测量错误,可能还会出现任意时滞。传统方法会低估或完全错过这种相关性,这并不罕见,并且起着重要的作用。由于传统的相似性度量无法捕获真实的关系,因此提出了一种简单的时滞捕获算法,该算法结合了一些现有的时滞和相似性度量技术,并具有并行实现的功能。使用诸如隔离实验条件和加权平均值之类的改进来获得更好的准确性,并为用户提供区分不同实验的灵活性。

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