Giant refractory solitary rectal ulcer syndrome treated with topical sucralfate.

摘要

Solitary rectal ulcer syndrome (SRUS) is a disorder of defecation with features of obstructed defecation, such as prolonged straining, tenesmus, and internal or external prolapse. It is an uncommon and under-diagnosed disorder, with an estimated annual incidence of one to 3.6 persons per 100,000 inhabitants. The pathogenesis of SRUS is not well understood, and apparently, multiple factors contribute to its development. The most accepted theories are related to direct trauma or local ischemia, such as prolonged straining at stool and difficulty initiating defecation, along with digital evacuation in persons with constipation or occult mucosal prolapsed.