Outcome of polyarteritis nodosa and churg‐strauss syndrome

摘要

AbstractObjective. To compare outcome in patients with polyarteritis nodosa (PAN) and patients with Churg‐Strauss syndrome (CSS) followed up at a single center.Methods. A retrospective data review of 13 patients with PAN and 12 patients with CSS who were followed up at a vasculitis clinic. Outcome measures included a global damage index, disability and pain dimensions of the Health Assessment Questionnaire, and mortality rate.Results. Compared with patients with CSS, patients with PAN had a significantly higher mean damage index score (5.15 versus 2.42;P= 0.011), a higher disability score (1.09 versus 0.16;P= 0.007), and a higher pain score (1.04 versus 0.01;P= 0.017). Patients with PAN had more relapses (relative risk = 5.07;P<0.000) and a higher mortality rate (31) compared with patients with CSS (8).Conclusion. PAN and CSS differ in their morbidity and mortality; therefore, they should be considered as distinct clinical entitie