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Descemet's stripping automated endothelial keratoplasty with anterior chamber intraocular lenses

机译:Descemet的带前房人工晶状体剥离的自动内皮角膜移植术

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We thank Mittal and Garg for their interest in our publication. Our study analysed Descemet's stripping automated endothe-lial keratoplasty (DSAEK) with anterior chamber intraocular lenses (ACIOL) with regards to 3-year graft survival and endothelial cell loss as our main outcome measures, not visual outcome or complications.1 Here, we used Kaplan-Meier survival analysis that takes into account any censored data from loss to follow-up, to derive that there was a significantly poorer graft survival in the DSAEK-ACIOL group versus the DSAEK group (log-rank p=0.002). In fact, completely excluding subjects with less than 3 years of follow-up as suggested by Mittal and Garg would actually lead to a selection bias, missing 14 (out of a possible total 19) graft failures and further strengthening our study conclusions-although in an inaccurate way.
机译:感谢米塔尔和加尔格对我们出版物的关注。我们的研究使用前房人工晶状体(ACIOL)来分析Descemet的剥离自动内皮细胞角膜移植术(DSAEK),并将其作为3年移植物存活率和内皮细胞损失的主要指标,而不是视觉结果或并发症。1在这里,我们使用了Kaplan-Meier生存分析考虑了从丢失到随访的所有检查数据,得出DSAEK-ACIOL组的移植物存活率比DSAEK组差得多(log-rank p = 0.002)。实际上,按照米塔尔和加尔格的建议,完全排除随访时间少于3年的受试者实际上会导致选择偏倚,错过14个(可能总共19个)移植失败,并进一步加强我们的研究结论-尽管一种不准确的方式。

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