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Efficacy of biotechnologically derived product in counteracting ill effects of aflatoxins in broiler chicken

机译:生物技术衍生产品在对抗肉鸡中黄曲霉毒素的不良影响中的功效

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摘要

A preliminary in-vitro aflatoxin adsorption study was conducted, and it was found that, the degradability of aflatoxin (AF) by the biotechnologically derived product (BTP) was similar to that of hydrated sodium calcium allumino-sillicate (HSCAS) and mannan ologosachharide (MOS). Further, an in-vivo trial was undertaken to assess BTP over HSCAS in broiler chicken fed diet containing aflatoxin (AF) with experimental design: T-1-basal diet; T-2-250 ppb ofAF; T-3-AF 250 ppb with HSCAS at 1 kg/ton; T-4 and T-5-AF 250 ppb with BTP 200 g/ton and 400 g/ton, respectively. During 42 days, trial revealed non-significant differences in performance parameters, dressing percentage, relative organ weights and serum biochemical parameters among treatments. Whereas, serum profile of ALT (P<0.01) and AST (P<0.05) was significantly increased with addition of AF (T-2) indicating limitation of toxicity only to cellular level at liver. Addition of BTP was found to normalize the increased ALT and AST levels.
机译:进行了体外黄曲霉毒素的初步吸附研究,结果发现,生物技术衍生产品(BTP)对黄曲霉毒素(AF)的降解性与水合铝硅尿酸钙钠(HSCAS)和甘露酸ologosachharide( MOS)。此外,还进行了一项体内试验,以试验设计的T-1基础日粮,含黄曲霉毒素(AF)的肉鸡饲喂日粮来评估HSCAS上的BTP。 T-2-250 ppb的AF;含HSCAS的T-3-AF 250 ppb,1千克/吨; T-4和T-5-AF 250 ppb,BTP分别为200克/吨和400克/吨。在42天中,试验显示治疗之间的性能参数,敷料百分比,相对器官重量和血清生化参数无显着差异。 ALT(P <0.01)和AST(P <0.05)的血清分布随AF(T-2)的添加而显着增加,表明毒性仅限于肝细胞水平。发现添加BTP可以使ALT和AST水平升高正常化。

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