Bovine viral diarrhoea(BVD) virus antiviral activity of Korean Tung Tree (Aleurites fordii) extracts in vivo

摘要

This study investigated the Bovine viral diarrhoea(BVD) virus antiviral effect of Aleurites fordii (tung tree) extract. First, a cytotoxicity test on MDBK (Madin-Darby bovine kidney) cells took place at various n -Hexane and ethyl acetate extract concentrations. Each of the extracts' cytotoxicity test results had 0.03mg/m1 of n -Hexane and 0.06 mg/ml of ethyl acetate. In the tissue culture infectious dose (TCID50) assay, 0.03 mg/ml of the ethyl acetate extracts decreased the BVD virus by 1.4 log, whereas the other extracts did not show any antiviral activity. The results suggest that ethyl acetate extracts and fractions of Aleurites fordii can replace chemical antivirus substances.