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首页> 外文期刊>International journal of clinical pharmacology and therapeutics >Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose antiinterleukin- 18 mAb GSK1070806 in healthy and obese subjects.

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose antiinterleukin- 18 mAb GSK1070806 in healthy and obese subjects.

机译：在健康和肥胖受试者中单剂量抗白介素18 mAb GSK1070806的安全性，耐受性，药代动力学和药效学。

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摘要

GSK1070806 warrants clinical investigation in patients.

机译：GSK1070806需要对患者进行临床研究。

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来源
《International journal of clinical pharmacology and therapeutics》 |2014年第10期|共13页
作者
Prafull Mistry; Juliet Reid; Isabelle Pouliquen; Simon McHugh; Lee Abberley; Stephen DeWall; Adam Taylor; Xin Tong; Marian Rocha Del Cura; Elizabeth McKie;
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正文语种 eng
中图分类毒物学（毒理学）;
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1. Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose antiinterleukin- 18 mAb GSK1070806 in healthy and obese subjects. [J] . Prafull Mistry, Juliet Reid, Isabelle Pouliquen, International journal of clinical pharmacology and therapeutics . 2014,第10期

机译：在健康和肥胖受试者中单剂量抗白介素18 mAb GSK1070806的安全性，耐受性，药代动力学和药效学。
2. Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of a Single-Dose of NN2211, a Long-Acting Glucagon-Like Peptide 1 Derivative, in Healthy Male Subjects. [J] . Elbrond B, Jakobsen G, Larsen S, Diabetes care . 2002,第8期

机译：在健康男性受试者中，单剂量NN2211（一种长效胰高血糖素样肽1衍生物）的药代动力学，药效学，安全性和耐受性。
3. PHARMACOKINETICS, SAFETY AND TOLERABILITY OF TEDIZOLID PHOSPHATE AFTER SINGLE-DOSE ADMINISTRATION IN HEALTHY KOREAN SUBJECTS. [J] . Kim Y., Kim A., Rhee S., Clinical Pharmacology and Therapeutics . 2016,第Suppla1期

机译：在健康韩国人中单剂量给药后，替替唑磷酸酯的药代动力学，安全性和耐受性。
4. Safety, tolerability, pharmacodynamics and pharmacokinetics following single subcutaneous dosesof a teverelix depot formulation in healthy male volunteers [C] . C. MacLean, F. Larsen, R. Piechatzek, Annual meeting exposition of the Controlled Release Society . 2005

机译：在健康男性志愿者中单次皮下注射Teverelix储库制剂后的安全性，耐受性，药效动力学和药代动力学
5. Beta-lactam antimicrobial dosing optimization in obese patients compared to non-obese patients using population pharmacokinetic/pharmacodynamic approach. [D] . Chung, Eun Kyoung. 2015

机译：使用群体药代动力学/药效学方法，与非肥胖患者相比，肥胖患者的β-内酰胺抗菌药物剂量优化。
6. Pharmacokinetics, pharmacodynamics, safety, and tolerability of single-dose denosumab in healthy Chinese volunteers: A randomized, single-blind, placebo-controlled study [O] . Qian Chen, Chaoying Hu, Yanmei Liu, 2012

机译：单剂量地诺单抗在健康中国志愿者中的药代动力学，药效学，安全性和耐受性：一项随机，单盲，安慰剂对照研究
7. Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting glucagon-like peptide 1 derivative, in healthy male subjects [O] . Elbrond, B., Jakobsen, G., Larsen, S., 2002

机译：单剂量NN2211（一种长效胰高血糖素样肽1衍生物）在健康男性受试者中的药代动力学，药效学，安全性和耐受性

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