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首页> 外文期刊>International Journal of Clinical Pharmacology Research >Effect of hyperthermic water bath on parameters of cellular immunity.
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Effect of hyperthermic water bath on parameters of cellular immunity.

机译:高温水浴对细胞免疫参数的影响。

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摘要

Effects of hyperthermic water bath on selected immune parameters (lymphocyte subpopulations, natural killer (NK) cell counts and their activity) were studied in a group of 10 volunteers. Application of hyperthermic water bath (both topical and whole-body) was followed by a significant reduction of relative B lymphocyte counts. Whole-body hyperthermic water bath reduced relative total T lymphocyte counts, increased relative CD8+ T lymphocyte and NK cell counts and increased NK activity. Whole-body hyperthermic bath increased somatotropic hormone (STH) activity in eight out of 10 volunteers; higher relative counts of CD8+ lymphocytes and NK cells were observed compared with the group of volunteers not responding to hyperthermic water bath by STH secretion. In five volunteers STH was released in response to local hyperthermic water bath and the NK activity of lymphocytes also increased but their relative counts did not. The results suggest that these increases in CD8+ lymphocyte and NK cell counts are probably dependent on increased STH production.
机译:在一组10名志愿者中研究了高温水浴对所选免疫参数(淋巴细胞亚群,自然杀伤(NK)细胞计数及其活性)的影响。应用高温水浴(局部和全身)后,相对B淋巴细胞计数显着降低。全身高温水浴减少了相对总T淋巴细胞计数,增加了相对CD8 + T淋巴细胞和NK细胞计数,并增加了NK活性。 10名志愿者中有8名使用全身高温浴提高了促生长激素(STH)活性;与通过STH分泌对热水浴无反应的志愿者组相比,观察到较高的CD8 +淋巴细胞和NK细胞相对计数。在五名志愿者中,STH是响应局部高温水浴而释放的,淋巴细胞的NK活性也增加了,但它们的相对计数却没有。结果表明,CD8 +淋巴细胞和NK细胞计数的这些增加可能取决于STH产生的增加。

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