Effects of genetic polymorphisms of CYP2C19*2/*3 and MDR1 C3435T on the pharmacokinetics of lansoprazole in healthy Chinese subjects.

Yu-Xin Zhang; Shi-Jie Wei; Xiao-Ying Yang; Wen-Ping Zhang; Xin-Yu Wang; Hong-Wan Dang

首页> 外文期刊>International journal of clinical pharmacology and therapeutics >Effects of genetic polymorphisms of CYP2C19*2/*3 and MDR1 C3435T on the pharmacokinetics of lansoprazole in healthy Chinese subjects.

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Effects of genetic polymorphisms of CYP2C192/3 and MDR1 C3435T on the pharmacokinetics of lansoprazole in healthy Chinese subjects.

机译：CYP2C19 * 2 / * 3和MDR1 C3435T基因多态性对兰索拉唑在中国健康受试者体内药代动力学的影响。

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摘要

CYP2C19*2/*3 and MDR1 C3435T polymorphisms are important determinants of LPZ pharmacokinetics.

机译：CYP2C19 * 2 / * 3和MDR1 C3435T多态性是LPZ药代动力学的重要决定因素。

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来源
《International journal of clinical pharmacology and therapeutics》 |2014年第10期|共6页
作者
Yu-Xin Zhang; Shi-Jie Wei; Xiao-Ying Yang; Wen-Ping Zhang; Xin-Yu Wang; Hong-Wan Dang;
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正文语种 eng
中图分类毒物学（毒理学）;
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1. Effects of genetic polymorphisms of CYP2C19*2/*3 and MDR1 C3435T on the pharmacokinetics of lansoprazole in healthy Chinese subjects. [J] . Yu-Xin Zhang, Shi-Jie Wei, Xiao-Ying Yang, International journal of clinical pharmacology and therapeutics . 2014,第10期

机译：CYP2C19 * 2 / * 3和MDR1 C3435T基因多态性对兰索拉唑在中国健康受试者体内药代动力学的影响。
2. A correlative study of polymorphisms of CYP2C19 and MDR1 C3435T with the pharmacokinetic profiles of lansoprazole and its main metabolites following single oral administration in healthy adult Chinese subjects [J] . Chang-Yin Li, Jun Zhang, Ji-Hong Chu, European journal of drug metabolism and pharmacokinetics . 2014,第2期

机译：CYP2C19和MDR1 C3435T基因多态性与兰索拉唑及其主要代谢产物药动学特征的单次口服相关研究
3. Effects of CYP2C19 polymorphism on the pharmacokinetics of lansoprazole and its main metabolites in healthy Chinese subjects. [J] . Zhang D, Wang X, Yang M, Xenobiotica: the fate of foreign compounds in biological systems . 2011,第6期

机译：CYP2C19基因多态性对健康人兰索拉唑及其主要代谢产物药代动力学的影响。
4. ASSOCIATION OF CYP3A4 * 18B POLYMORPHISMS WITH THE PHARMACOKINETICS OF TACROLIMUS IN CHINESE RENAL TRANSPLANT RECIPIENTS [C] . Li Danying, Fang Yun, Teng Ruichen Progress on post-genome technologies and modern natural products . 2011

机译：CYP3A4 * 18B多态性与中国肾移植患者滑石M药代动力学的关系
5. The Inflammatory Effects of Glucose and Lipids on Granulocytes and Monocytes of Healthy, Obese, and Type II Diabetic Subjects. [D] . Horvath, Peter. 2013

机译：葡萄糖和脂质对健康，肥胖和II型糖尿病受试者的粒细胞和单核细胞的炎症作用。
6. The effect of CYP2C19 polymorphism on the pharmacokinetics and acid-inhibitory effects of oral lansoprazole and omeprazole [O] . C H J Bekkers, D J Touw, C B H W Lamers, 2002

机译：CYP2C19基因多态性对口服兰索拉唑和奥美拉唑的药代动力学和抑酸作用的影响
7. GW25-e0251 Genetic polymorphisms of CYP2C19*2 and ABCB1 C3435T affect the pharmacokinetics and pharmacodynamics response to clopidogrel in patients with acute coronary syndrome in the Chinese Han population [O] . Xiaqin Wang, Bangnin Wang 2014

机译：GW25-e0251 CYP2C19 * 2和ABCB1 C3435T的遗传多态性影响中国汉族人群急性冠脉综合征患者对氯吡格雷的药代动力学和药效学反应

Effects of genetic polymorphisms of CYP2C19*2/*3 and MDR1 C3435T on the pharmacokinetics of lansoprazole in healthy Chinese subjects.

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Effects of genetic polymorphisms of CYP2C192/3 and MDR1 C3435T on the pharmacokinetics of lansoprazole in healthy Chinese subjects.