The present study aimed to determine the total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) and antimicrobial activity of Cerioporus varius (Pers.) Zmitr. Kovalenko mushrooms collected in Gaziantep province, Turkey. The TAS, TOS and OSI of the mushroom were analyzed with Rel Assay Diagnostics kits. Antimicrobial activity of the mushroom was tested on 6 bacteria and 3 fungus strains with the modified agar dilution method. It was determined that the TAS of C. varius was 2.312±0.137, the TOS was 14.358±0.174 and the OSI was 0.627±0.047. Furthermore, it was determined that EtOH, MeOH and DCM mushroom extracts exhibited antimicrobial activities against the tested bacterial and fungal strains. In conclusion, it was determined that C. varius can be used as a natural antioxidant and antimicrobial source.
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