Prognostic value of glucosylceramide synthase and P-glycoprotein expression in oral cavity cancer

Kim Ji Won; Park Yangsoon; Roh Jong-Lyel; Cho Kyung-Ja; Choi Seung-Ho; Nam Soon Yuhl; Kim Sang Yoon

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Prognostic value of glucosylceramide synthase and P-glycoprotein expression in oral cavity cancer

机译：葡糖神经酰胺合酶和P-糖蛋白表达在口腔癌中的预后价值

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摘要

Glucosylceramide synthase (GCS) and P-glycoprotein (P-gp) overexpression are associated with multidrug resistance in several human cancers. This study investigated the prognostic value of GCS and P-gp in oral cavity squamous cell carcinoma (OSCC).

机译：葡萄糖基神经酰胺合酶（GCS）和P-糖蛋白（P-gp）的过度表达与几种人类癌症的多药耐药性有关。这项研究调查了GCS和P-gp在口腔鳞状细胞癌（OSCC）中的预后价值。

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《International journal of clinical oncology》 |2016年第5期|共7页
作者
Kim Ji Won; Park Yangsoon; Roh Jong-Lyel; Cho Kyung-Ja; Choi Seung-Ho; Nam Soon Yuhl; Kim Sang Yoon;
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正文语种 eng
中图分类肿瘤学;
关键词
Oral cavity cancer; Glucosylceramide synthase; P-glycoprotein; Prognosis; Biomarker;

机译：口腔癌;糖基神经酰胺合酶;P-糖蛋白;预后;生物标志物;

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1. Prognostic value of glucosylceramide synthase and P-glycoprotein expression in oral cavity cancer [J] . Kim Ji Won, Park Yangsoon, Roh Jong-Lyel, International journal of clinical oncology . 2016,第5期

机译：葡糖神经酰胺合酶和P-糖蛋白表达在口腔癌中的预后价值
2. Reduced UDP-glucose Levels Are Associated with P-glycoprotein Over-expression in L1210 Cells and Limit Glucosylceramide Synthase Activity [J] . Turakova Katarina, Pavlikova Lucia, Messingerova Lucia, Anticancer Research: International Journal of Cancer Research and Treatment . 2015,第5期

机译：降低的UDP葡萄糖水平与L1210细胞中的P-糖蛋白过表达和限制葡萄糖基神经酰胺合酶活性相关
3. Resistance to the antiproliferative effect induced. by a short-chain ceramlde Is associated with an increase of glucosylceramide synthase, P-glycoprotein, and multidrug-resistance gene-1 in cervical cancer cells [J] . Gisela Giitierrez-Iglesias, Yamiec Hurtado, Icela Palma-Lara, Cancer chemotherapy and pharmacology. . 2014,第4期

机译：抗诱导的抗增殖作用。短链ceramlde与宫颈癌细胞中糖基神经酰胺合酶，P-糖蛋白和多药耐药基因-1的增加有关
4. Relationship between scintimammography of breast cancer and the expression of P-glycoprotein and GST- π in BREAST CANCER [C] . The First China-Japan-Korea conference of nuclear medicine . 2002

机译：乳腺癌闪烁成像与乳腺癌中P-糖蛋白和GST-π表达的关系
5. Role of glucosylceramide synthase (GCS) in cancer metastasis, stem cell behavior and cell proliferation. [D] . Bhinge, Kaustubh N. 2012

机译：葡糖神经酰胺合酶（GCS）在癌症转移，干细胞行为和细胞增殖中的作用。
6. Prognostic value of using glucosylceramide synthase and cytochrome P450 family 1 subfamily A1 expression levels for patients with triple-negative breast cancer following neoadjuvant chemotherapy [O] . Jiannan Liu, Shuhua Wang, Congcong Wang, 2021

机译：使用葡萄糖苷酰胺合成酶和细胞色素P450家族的预后价值1新辅助化疗后三阴性乳腺癌患者的亚家族A表达水平
7. Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells [O] . Yong-yu Liu, Tie-yan Han, O E. Giuliano, 1999

机译：糖基神经酰胺合酶的表达，将神经酰胺转化为糖基神经酰胺，赋予人乳腺癌细胞以阿霉素耐药性

Prognostic value of glucosylceramide synthase and P-glycoprotein expression in oral cavity cancer

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