Effect of Desferal Drug and Green Tea on the Levels of Lipid Prophile in Sera of Rabbits Induced Diabetes Mellitus by Iron Overload

摘要

Iron is an essential nutrient and when it is present in excess, iron's toxicity is largely on it is ability to catalyze the generation of radicals which attack and damage cellular macromolecules. The present study is an attempt to confirm that hyperprotememia, diabetes, and iron overload are members of oxidative stress, which may able us to compare the treatment between green tea and desferal drug in sera of rabbits induced with diabetes mellitus. Fourteen male rabbits divided into two groups, one ascontrol diet (n=5), the other (n=9) with control diet in addition to ferrosam. While the treatment of 2nd group after three months of experimental conditions done by green tea to one subgroup (n=5) and the other subgroup (n=4) with desferal. The resultsrevealed that treatment with green tea can prevent the effect of iron overload on the antioxidant levels and other biological parameters at the same action of desferal.