Synthesis and Preliminary Results on the Catalytic Activity of Metal Complexes obtained from C-2-Symmetric Ligands Derived from R-(+)-Betti base

摘要

The enantiopure 1-(a-aminobenzyl)-2-naphthol, known as Betti base, was used for the synthesis of some novel compounds which show a C-2-symmetry. Some of these compounds, after derivatization, were used as ligands in association with transition metals to prepare complexes which have been tested as catalysts for enantioselective reactions. Aminoalcohol (Salantype) derivatives of these compounds were obtained upon reduction and it was also possible to obtain complexes with transition metals such as Mn, Ni, Co and Cu. Furthermore a novel 6-membered analogue bisoxazoline ligand, the 2,6-bis((R)-1Phenyl-1H-naphtho1,2-e1,3 oxazin-3-yl) pyridine, was obtained and two Cu-complexes were prepared. As preliminary results the metal complexes gave up to discrete values of asymmetric induction.