Relation between axial length of the eye and hypotensive effect of latanoprost in primary open angle glaucoma.

摘要

AIMS: To study the effect of axial length on the hypotensive effect of latanoprost in primary open angle glaucoma (POAG) in a prospective, observational study. METHODS: The authors measured axial length and baseline intraocular pressure (IOP) of 109 eyes with POAG, and then repeated the IOP measurements at 1, 3, and 6 months after starting treatment with latanoprost. RESULTS: The mean IOP level was significantly lower in eyes with a shorter axial length compared with the eyes with a longer axial length both at 3 and 6 months of treatment (p = 0.03 and p = 0.04, respectively, ANOVA). CONCLUSION: The hypotensive effect resulting from treatment with latanoprost could be related to ocular axial length.