A Highly Efficient Synthesis of Pyrrolo1,2-apyrimidine Derivatives Containing 1,3-Indandione Skeleton

摘要

abstract_textpThe pyrimidines fused with pyrrole ring, pyrrolopyrimidines, showed broad applicability in medicinal chemistry. Herein, we synthesized the new derivatives (8 examples) of pyrrolo1,2-apyrimidine containing 1,3-indandione skeleton by the use of triethylammonium thiolates, methyl iodide, and ketene aminals via a one-pot three-component reaction./p/abstract_text